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In addition, lactylation exacerbates the inflammatory response in SLE patients by regulating the type I interferon pathway and inflammatory signaling pathways such as the NF-ΞΊB pathway (94), lactylation can enhance the nuclear translocation of IRF3 and NF-ΞΊB, thereby promoting the secretion of pro-inflammatory cytokines such as TNF-Ξ±, IL-6
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[DOI] [PubMed] [Google Scholar] 36.McBean G.J
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